Judith A Clements Selected Research

Kallikreins (Kallikrein)

11/2020	KLK4 Induces Anti-Tumor Effects in Human Xenograft Mouse Models of Orthotopic and Metastatic Prostate Cancer.
1/2020	The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.
1/2019	MicroRNA-3162-5p-Mediated Crosstalk between Kallikrein Family Members Including Prostate-Specific Antigen in Prostate Cancer.
1/2018	Kallikrein-related peptidases represent attractive therapeutic targets for ovarian cancer.
1/2018	Mining human cancer datasets for kallikrein expression in cancer: the 'KLK-CANMAP' Shiny web tool.
1/2017	Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases.
12/2016	Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors.
12/2016	In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B.
1/2016	Prostate Cancer-Associated Kallikrein-Related Peptidase 4 Activates Matrix Metalloproteinase-1 and Thrombospondin-1.
10/2014	Kallikrein-Related Peptidases in Prostate Cancer: From Molecular Function to Clinical Application.

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Judith A Clements Research Topics

Disease

64	Prostatic Neoplasms (Prostate Cancer) 07/2021 - 01/2004
55	Neoplasms (Cancer) 07/2021 - 05/2003
17	Neoplasm Metastasis (Metastasis) 01/2021 - 07/2010
13	Ovarian Neoplasms (Ovarian Cancer) 01/2019 - 05/2010
5	Carcinogenesis 01/2019 - 11/2010
4	Ovarian Epithelial Carcinoma 01/2013 - 05/2003
3	Disease Progression 01/2014 - 01/2004
2	Ascites 01/2013 - 04/2010
1	Lymphatic Metastasis 11/2019
1	Hypoxia (Hypoxemia) 01/2019
1	Skin Diseases (Skin Disease) 12/2016
1	Netherton Syndrome 12/2016
1	Pain (Aches) 09/2015
1	Inflammation (Inflammations) 09/2014
1	Bone Resorption 01/2013

Drug/Important Bio-Agent (IBA)

36	Kallikreins (Kallikrein)IBA 11/2020 - 05/2003
29	Peptide Hydrolases (Proteases)FDA Link 11/2020 - 06/2006
17	Biomarkers (Surrogate Marker)IBA 01/2019 - 05/2003
15	Serine Proteases (Serine Protease)IBA 01/2020 - 06/2006
15	Proteins (Proteins, Gene)FDA Link 11/2019 - 06/2006
15	Prostate-Specific Antigen (Semenogelase)IBA 01/2019 - 01/2004
12	AndrogensIBA 01/2021 - 03/2008
10	Hormones (Hormone)IBA 01/2021 - 01/2004
8	Pharmaceutical PreparationsIBA 01/2021 - 07/2010
7	Androgen Receptors (Androgen Receptor)IBA 01/2019 - 05/2007
7	Paclitaxel (Taxol)FDA LinkGeneric 02/2014 - 04/2010
6	MicroRNAs (MicroRNA)IBA 07/2021 - 04/2015
6	IntegrinsIBA 10/2013 - 08/2009
6	EnzymesIBA 10/2010 - 05/2003
5	kallikrein 4IBA 01/2013 - 03/2007
4	Messenger RNA (mRNA)IBA 03/2019 - 06/2006
4	HydrogelsIBA 01/2019 - 11/2010
4	Genetic Markers (Genetic Marker)IBA 01/2018 - 01/2011
4	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 04/2011
4	Matrix Metalloproteinases (MMPs)IBA 01/2017 - 09/2009
3	enzalutamideIBA 01/2021 - 12/2015
3	Biological ProductsIBA 01/2018 - 04/2014
3	RNA (Ribonucleic Acid)IBA 12/2017 - 07/2010
2	bicalutamide (Casodex)FDA LinkGeneric 01/2021 - 12/2015
2	Tumor Biomarkers (Tumor Markers)IBA 01/2018 - 05/2003
2	ProteomeIBA 02/2014 - 02/2007
2	Tissue Kallikreins (Tissue Kallikrein)IBA 07/2013 - 01/2007
2	LigandsIBA 07/2012 - 08/2011
2	Protein Isoforms (Isoforms)IBA 04/2011 - 06/2006
2	Transcription Factors (Transcription Factor)IBA 01/2011 - 05/2010
2	SteroidsIBA 05/2010 - 01/2009
2	TrypsinIBA 06/2008 - 05/2008
1	Androgen Antagonists (Antiandrogens)IBA 01/2021
1	plastochromanol 8IBA 03/2019
1	Vitamin E FDA LinkGeneric 03/2019
1	Insulin (Novolin)FDA Link 01/2019
1	CollagenIBA 01/2019
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2019
1	Amino Acids FDA Link 01/2019
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2019
1	Alkaline PhosphataseIBA 01/2019
1	TensinsIBA 01/2019
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2019
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2019
1	Phosphotransferases (Kinase)IBA 01/2019
1	Tricarboxylic AcidsIBA 01/2019
1	Protein Kinases (Protein Kinase)IBA 01/2019
1	TOR Serine-Threonine KinasesIBA 01/2019
1	Long Noncoding RNAIBA 12/2017
1	Interleukin-8 (Interleukin 8)IBA 10/2017
1	Fibroblast Growth Factor 1 (FGF-1)IBA 10/2017
1	hepsinIBA 01/2017
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 12/2016
1	Cathepsin BIBA 01/2016
1	Cholecystokinin (Pancreozymin)IBA 01/2016
1	Peptide Hormones (Polypeptide Hormones)IBA 01/2016
1	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 01/2016
1	Death Domain ReceptorsIBA 01/2016
1	Insulin-Like Growth Factor I (IGF-1)IBA 09/2015
1	Insulin-Like PeptidesIBA 09/2015
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2015
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2015
1	P-2 (P 2)IBA 04/2015
1	3' Untranslated Regions (3' UTR)IBA 04/2015
1	Indicators and Reagents (Reagents)IBA 09/2014
1	Serine (L-Serine)FDA Link 09/2014
1	LuciferasesIBA 04/2014
1	Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA 02/2014
1	Telomerase (Telomerase Reverse Transcriptase)IBA 06/2013
1	SuspensionsIBA 01/2013
1	Plasminogen Activators (Plasminogen Activator)IBA 01/2013
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 01/2013
1	MineralsIBA 01/2013
1	Sex Hormone-Binding GlobulinIBA 07/2012
1	Testosterone (Sustanon)FDA Link 07/2012
1	Glutathione Transferase (Glutathione S-Transferase)IBA 07/2012
1	ErbB Receptors (EGF Receptor)IBA 03/2012
1	Epidermal Growth Factor (EGF)IBA 03/2012
1	Protein Sorting Signals (Signal Peptide)IBA 02/2012
1	LipidsIBA 02/2012
1	Peptides (Polypeptides)IBA 02/2012

Therapy/Procedure

9	Therapeutics 01/2021 - 08/2009
2	Drug Therapy (Chemotherapy) 01/2014 - 04/2010
2	Prostatectomy (Retropubic Prostatectomy) 04/2012 - 07/2010
1	Precision Medicine 10/2016